Virus Disinfection and Population Genetics: Toward the Control of Waterborne Virus Diseases by Water Engineering

Abstract Purpose of Review Major waterborne viruses comprise numerous variants rather than only a master sequence and form genetically diverse population. High genetic diversity is advantageous for adaptation to environmental changes because the highly population likely includes resistant an adverse effect. Disinfection broadly employed tool inactivate pathogens, but due virus evolvability, may not be inactivated sufficiently in currently applied disinfection conditions. Here, by focusing on genetics, we explore possibility factor emergence sensitivity change. Recent Findings To test whether obtains resistance, evolutionary experiment developed field genetics has been applied, indicating change sensitivity. It also confirmed that strains lower laboratory strains. In some these studies, within less sensitive higher. Researches have shown contribution intra-population phenotype, so attribute diversity. Summary The research elucidating relationship between evolution recently begun, significant information about accumulated. develop effective strategy control spread, need clarify practice truly affects outbreaks refining both experiments related disinfection-exerted environment.